TCM Achievements in Treating Primary Glomerulonephritis

1. A little girl, 12 years old, Systemic edema and oliguria for over 10 days . The edema started from the eyelids, then involved in the

whole body . Low fever, slight cough, loose stool . Floating-full pulse and thin-yellowish tongue coating . Uroscopy: protein ( + + + ) , RBC 0 1 , WBC a few . Temperature 38℃, Bp 19 .5/ 13 .33 kPa . This syndrome is caused by wind attacking the lung and exterior combined with water-pathogen . Dispelling wind and disper sing lung-Qi to expel the pathogens upwards, removing damp and promoting diures is to reduce the pathogens downwards, thus the water must be isolated.

Only after one week treatment, In the second visit: Edema and low fever have relieved, and stool has been restored normally, but there still is a poor appetite . Uroscopy: protein ( + ) , Bp 17 .5∕ 13 kPa . The spleen and kidney would be regulated while wind and water have been removed, so strengthening the spleen and kidney are the therapeutic rule.

After taking one recipe modified from the previous for over 10 doses, her Bp lowered to a normal level and albumen in urine become negative . The disease didn’ t relapse yet through 2 years follow-up survey . This is TCM’s POWER!

2. a lady, 20 years old . Edema of the whole body for half of a year, accompanied with amenorrhea . After treatment , the facial

edema reduced but serious edema still below the waist and abdomen, shifting dullness in abdomen, inability of the dented skin on lower limb to be restored at once while pressing, emaciation, sallow complexion and thready-feeble pulse . Protein in urine ( + + + ) . Those indicate the blood has become water-pathogen, and should be treated with promoting blood flow to resolve blood stasis .

After taking a recipe for one month, ascites and edema of the lower limbs have gradually relieved, complexion become red, but no menstruating yet .Uroscopy: Protein ( + + ) , RBC ( + ) , granule cast ( + ) . The primary recipe is added with Dahuang Zhechong Wan ( pill ) 9 g, which is divided into two equal parts and swallowed twice a day . One week later , menstruating with profuse purplish blood mixed by clots, and then edema relieved rapidly . Uroscopy: Protein ( + ) , RBC ( – ) , granule cast ( – ) . The therapeutic rule is changed into regulating both Qi and blood and reinforcing Qi . It was told in a letter afterwards that proteinuria had relieved, she had recover completely and had her baby healthily .

3. A lady Zhou, female, 41 years old . Suffering from chronic nephritis for 10 years and acute attack usually due to exogenous affection or overtrain . 10 days ago, aversion to cold with fever , nausea, vomiting right after eating, etc . appeared due to exoge-

nous af fection . After symptomatic treatment the most symptoms above-mentioned have been obviously reduced, but such symptoms as oliguria, edema, heavy sensation of the limbs, dizziness and distending feeling in the head, nausea and vomiting are getting more and more serious . Examination after admission to the hospital : Lassitude of both physique and mind, edema in the face and head, puffy and bright eyelids like the lying silkworm, enlarged abdomen, edema of the lower extremities with inability

of the dented skin to be restored at once while pressing, rough skin, dry nails, red tongue with thin-yellowish coating and deep-thready-rapid pulse . Bp 24/ 13 .5 kPa; routine uroscopy: urinary protein ( + + + + ) , WBC 46 , RBC 4 6 , epithelial cell 1 2 and granular cast 0 1 ; blood examination: WBC 1 .2×109 , N 0 .72, L 0. 28, HGB 92 g / L; PSP test, excretion 2% for 15 minutes and excretion 32% for 2 hours; plasma albumin 26 g / L, globulin 18 g / L .

It belongs to syndrome of water retention with exterior excess and depressed heat, caused by spleen -deficiency with endogenous damp and newly exogenous af fection, resulting in failure of both Qi to disperse outward and the spleen to transform and transport, further internal stagnation of water-damp pathogen . Accordingly, it should be treated by relieving the exterior syndrome and

eliminating the interior pathogens, i .e . inducing diaphoresis and diuresis, and Yuebi Jiazhu Tang ( decoction) combined with Mahuang Lianyao Chixiaodou Tang ( decoction) would be chosen to be used so that Qi-movement in the Sanjiao can be unobstructed and the external and internal damp-pathogen can be dispelled respectively .

After taking 7 dosages of TCM medicine, she got much better, manifested as edema of the face and eyelids relieved,

headache, dizziness, nausea and vomiting all disappeared, and feeling vigorous and strong . Routine uroscopy reexamination: all indexes are improved markedly . Although she had got better , several days later she was invaded by exopathogen again, presenting spontaneous sweating , often aversion to wind, systemic soreness, muscular aching, heavy limbs, feeble-rapid pulse and red tongue with whitish coating . It is certainly attributed to type of interior damp with exterior deficiency resulting

from a repeated af fection on the basis of wind-damp pathogen unlieved, and is identical with her medical history , and therefore Jiawei Fangji Huangqi Tang ( decoction) was used to invigorate the spleen for replenishing the body surface and reduce damp-heat by diuresis . She was discharged from hospital after recovery when she had taken 20 doses of medicines .

4. A gentleman Cui , male, 29 years old . The patient was found urinary protein ( + + + ) in examination due to edema of the lower limbs, and thus diagnosed as chronic nephritis . The edema was relieved after being treated with Chinese herbal drugs, hormone,

immunosuppressants and so on, but uroscopy showed constantly abnormal , urinary protein ( + + + ) , quantity of urinary protein for 24 hours 5 g, and hormone was still used 10 mg a day while admission to the hospital .He had lumbar sorenes s and distension, dry throat with uncomfortable feeling, slight lassitude, insomnia, reddish tongue with thin yellowish and a little greasy coating,

taut-rolling pulse but forceless while deep pulse-taking . He suffers usually from common cold . This was diagnosed as consumptive disease and treated mainly with strengthening Qi and nourishing kidney-Yin . After a period of treatment, the symptoms of kidney- deficiency such as lumbar soreness and others were reduced, and hormone was gradually stopped to be used; however, his

lassitude got gradually serious and felt limbs heavier which was aggravated while motion, accompanied with nausea, poor appetite, soft stool , dry throat with uncomfortable feeling, red tip of tongue with thin-whitish-greasy coating and thready-taut pulse with a little rolling . It belongs to deficiency of spleen-Qi with deficiency of spleen-Yin complicated with damp-pathogen, and thus

was treated by reinforcing Qi to invigorate the spleen and nourishing Yin to induce diuresis, and corresponding modified Shenling Baizhu San (powder) . Persist in using a prescription for three month the symptoms have basically disappeared excepting lassitude reduced, and urinary protein lowered to ( + ) , quantity of urinary protein for 24 hours lowered to 1 g . Then the patient left hospital due to improvement of the disease .

5. A lady Liu, female, 41 years old, cadre . The first vis it on 8 th of Sept ., 1999 . The patient has suffered from chronic nephritis for

30 years, manifested as dizziness, lassitude, soreness and weakness in waist and knees, pain in heel , eczema with iching on the skin of limbs and liability usually to common cold with sore throat . She was treated with persantine, indomethcin and Chinese herbal medicines in the other hospitals, however , there was no effectiveness . Urinary protein contant ( + + + ) , pale and puffy tongue

with teeth prints and thin-yellowish coating , and thready-rolling pulse . It belongs to syndrome of deficiency of both the spleen and kidney with exterior weakness and retention of damp-heat , and should be treated by reinforcing Qi to replenish the body surface and regulating-tonifying the spleen and kidney as the principal therapy, and eliminating damp-heat by promoting diuresis as the secondary one .

Above recipe modified had been ceaselessly used 12 months excepting use of Qingli Fang due to acute infection of the throat for a short time, and then all symptoms had been relieved and urinary protein gradually converted into the negative . Reexamination on 6 th of Sept . , 2010: quantity of urinary protein for 24 hours lowered from 2 .81 g before treatment to 0 .75 g , creatinine lowered from 127 .30μmol / L before treatment to 117 . 57μ mol / L , creatinine clearance rate raised from 5 5 .6 ml / min before treatment to 72 ml / min, the disease has basically relieved .

6. A lady Zhang, female, 20 years old, school leaver . The first vis it on 20 th of June, 1993 . The patient worked in a farm before and came back to Shanghai to seek medical advice since she had a remarkable general edema induced by skin infection and the

treatment in the local hospital was ineffective . She had a pale complexion, evident edema in the face and lower extremities, and cured sores on the skin .Uroscopy: protein( + + ) , RBC 3 4 , WBC ( + ) , granule cast 1 2 . Cholesterol 15 .86 mmol / L, total protein 41 g / L, albumin 2 .2 g / L, globumin 19 g / L, creatinine 114 .04μmol / L, carbon dioxide combining power 14 .08 mmol / L . After

treating by dispersing lung-Qi, invigorating the spleen, promoting diuresis and so on, edema had relieved, and urinary protein fluctuated around ( + + ) ( + + + ) with inability to be imporved after continuing treatment by the method of warming the kidney to induce astringency . Up to 4th of Feb ., 1994, the exudative sores of the lower limbs due to skin infection relapsed, accompanied with local burning sensation . Check right away: cholesterol 5 . 2 mmol / L, creatinine 79 .56μmol / L, carbon dioxide combining power 22 .0 mmol / L . Uroscopy: protein ( + + ) , RBC 0 1 , WBC 0 1 . It pertains to syndrome of kidney-deficiency with internal retention of damp-heat, and was treated by our recipe. The exudative sores relieved and routine uroscopy restored to the normal after administered above remedy for one week, and continuously consolidated treatment had not been stopped until approximately 6 months . It hasn’t recurred by follow-up survey for 3 years .

Under translation and will add more soon………